RESEARCH ARTICLE


Clinical Significance and Analytical Determination of Trace Amounts of Selenium in Human Blood - Spectrophotometeric Technique



Ranjana S. Khanna1, Reena Negi2, Deepti Pande2, Hari D. Khanna2, *
1 Department of Biophysics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221 005, India.
2 Department of Biophysics, Institute of Medical Sciences Banaras Hindu University, Varanasi – 221 005, India


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© 2010 Khanna et al.;

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Correspondence: * Address correspondence to this author at the Department of Biophysics, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221 005, India. Tel: +91-9450710446; Fax: +91-542-2367568; E-mail: hdkhanna@yahoo.co.in


Abstract

Selenium is an essential trace element that is important in proper immune system functioning and in free radical control. Selenium protects against heart weakness and degeneration. It is crucial for optimal health and detoxification. Selenium is required for the production of thyroid hormones. The body only needs a small amount. Nevertheless, the selenium mineral is an essential mineral which the body requires on a daily basis. The objective of the work concerns the proposal and development of the technique for the measurement of selenium levels in the human blood samples by a simple spectrophotometeric determination in diseased and health conditions.

Keywords: Selenium determination, Clinical significance, Spectrophotometeric method..